Neue Publikationen/new publications:
Gast, A., Werner, C., Niefind, K., Jose J. (2026). Functional characterization of 42 CK2α de novo variants associated with Okur-Chung neurodevelopmental syndrome. FEBS J., in press.
Werner, C., Barthel, T., Harasimowicz, H., Marminon, C., Weiss, M. S., Le Borgne, M., Niefind, K. (2026). Crystallographic Fragment Screening with CK2α’, an Isoform of Human Protein Kinase CK2 Catalytic Subunit, and Its Use to Obtain a CK2α’/Heparin Complex Structure. Kinases Phosphatases 4, 1.
Kasperowicz, S., Werner, C., Podsiadła-Białoskórska, M., Szołajska, E., Maciejewska, A. M., Lindenblatt, D., Niefind, K., Poznański, J., Winiewska-Szajewska, M. (2026). Novel fluoro-brominated benzotriazoles as potential CK2 inhibitors. How does fluorination affect the properties of benzotriazoles? Bioorg. Chem. 169, 109446.
Ortín, I., Ochoa-Callejero, L., Werner, C., Lindenblatt, D., Niefind, K., Martínez, A., de Pascual-Teresa, B., Ramos, A. (2025). Targeting Casein Kinase 2 and Histone Deacetylase with a Dual Inhibitor Effectively Reduces Tumor Growth in a Triple-Negative Breast Cancer Xenograft Model. ACS Pharmacol. Transl. Sci. 8, 2093-2105.
Niefind, K., Götz, C., Jose, J. (2025). 70 years of CK2: still exciting, essential - and enigmatic! Biol. Chem. 406, 65-67.
Werner, C., Eimermacher, S., Harasimowicz, H., Fischer, D., Pietsch, M., Niefind, K. (2025). A CK2α' mutant indicating why CK2α and CK2α', the isoforms of the catalytic subunit of human protein kinase CK2, deviate in affinity to CK2β. Biol. Chem. 406, 101-115.
Marminon, C., Werner, C., Gast, A., Herfindal, L., Charles, J., Lindenblatt, D., Aichele, D., Mularoni, A., Døskeland, S. O., Jose, J., Niefind, K., Le Borgne, M. (2025). Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2. Biol. Chem. 406, 125-138.