Neue Publikationen/new publications:
Rumler, H., Schmithals, C., Werner, C., Bollacke, A., Aichele, D., Götz, C., Niefind, K., Wünsch, B., Jose, J. (2024). Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthesis, Biological Evaluation, and Structural Studies on E-/Z-Isomers. ACS Pharmacol. Transl. Sci.
Werner, C., Lindenblatt, D., Viht, K., Uri, A., Niefind, K. (2023). Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2α′Cys336Ser as an Exquisite Crystallographic Tool. Kinases Phosphatases 1, 306-322
Voss, M., Cseke, L. J., Gassmann, W., Niefind, K. (2023). A splicing variant of EDS1 from Vitis vinifera forms homodimers but no heterodimers with PAD4. Protein Sci. 32, e4624
C. Werner, A. Gast, D. Lindenblatt, A. Nickelsen, K. Niefind, J. Jose, J. Hochscherf (2022). Structural Basis of Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2αLys198Arg. Front. Mol. Biosci. 9, 831693
D. Lindenblatt, V. Applegate, A. Nickelsen, M. Klußmann, I. Neundorf, C. Götz, J. Jose & K. Niefind (2022). Molecular Plasticity of Crystalline CK2α′ Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. J. Med. Chem. 65, 1302-1312